New study reveals how immune cells play a key role in movement

In a groundbreaking collaborative study supported by Rosetrees, scientists from Imperial College London and the University of Copenhagen have unveiled a novel mechanism by which specialised macrophages control muscle contraction and locomotion. Their discovery contrasts with the previous assumption that movement is only controlled by the nervous system. The researchers identified a macrophage population, known…

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Rosetrees and Race Against Dementia team up to drive out dementia

Six outstanding UK dementia teams funded through new £4.2m programme Together with Race Against Dementia, Rosetrees is proud to announce funding for six top UK dementia teams researching treatments or ways to prevent dementia.   70 teams from across the UK applied to the Race Against Dementia Teams Award launched in June 2023. Through a rigorous…

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New study reveals molecular causes of rare neurological condition in children

A new study led by Rosetrees-funded scientists at UCL Queen Square Institute of Neurology has identified the molecular defects underlying a complex developmental brain condition in children. The researchers investigated the role of a specific regulatory protein in the brain known as acyl-CoA-binding domain-containing protein 6, or ACBD6. Up until now, the implication of defects…

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Rosetrees intermediate and major project grant round now open!

Rosetrees is delighted to invite applications for project grants across the whole spectrum of bio-medical research. However, we are particularly (though not exclusively) interested in projects that address unmet clinical needs in the areas of mental health, eczema, pain, sleep and infertility. As we have a fixed global budget to cover all the projects, applications…

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Stem cell-derived model of the post-implantation human embryo

Researchers at the University of Cambridge and in the U.S. have created an embryo-like model from human stem cells to better understand post-implantation embryo development. This 3D structure derived from pluripotent stem cells replicates some developmental processes that occur in early human embryos. With this model, researchers can now probe key questions of human post-implantation…

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Genetic Clues Reveal Lung Cancer’s Next Move

   Knowing whether a tumour might grow or spread to other parts of a patient’s body could be key to survival – and now scientists are one step closer to unlocking the ability to predict just that. In a series of seven papers published today (Weds April 12) in Nature and Nature Medicine, Cancer Research…

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The Riddle of Cachexia

Scientists examining the causes of cachexia – the sudden loss of weight, appetite, and muscle that some cancer patients experience in the later stages of the disease – believe they are now one step closer to understanding the causes behind the condition. The study, part of the Cancer Research UK TRACERx programme, and published in…

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New study reveals how skin cancer resists treatment

Scientists have discovered how some skin cancers stop responding to treatment at the end of life. An in-depth analysis of 14 patients who died from incurable melanoma has revealed that changes to the order, structure and number of copies of tumour DNA could cause some skin cancers to resist treatment. These changes also explain how…

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VIRTUAL REALITY TRANSFORMS EDI TRAINING

Chelsea and Westminster Hospital NHS Foundation Trust has successfully used virtual reality (VR) technology for the first time to provide immersive learning experiences for staff in equality, diversity and inclusion training. The pilot project, in partnership with leading VR company Kiin,  has shown overwhelmingly positive results, with 97% of participants saying they would recommend the…

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